Real-Time Measurement and Control of Nutrients and Metabolites in Mammalian Cell Culture Process
Intellicentic currently offers a real-time solution to monitor the concentration of critical cell culture matrix components such as glucose and lactate in-situ. The Raman Spectroscopy base solution is autoclavable, non-destructive, and generally developed so that it can be customized to multiple cell lines or media types. Standard operational procedures for the use of the real-time measurement solution are available, and can be easily be adapted to comply with any prescribed quality system. Protocols and training explaining how to customize the solution to new cell lines and media types are also available. The real time prediction can be used as part of a traditional control or an advanced control strategy to improve the robustness and efficiency of mammalian cell cultures.